His return at Wembley on Wednesday would be a huge boost for Tottenham, given Kane has scored five goals in three European games so far.
However, former Liverpool Real Madrid midfielder McManaman claimed that he would ignore signing Kane and look to lure a younger player such as 18-year-old Kylian Mbappe to Madrid.
Tripper picked out Alli from the right, and the England man directed beyond Casilla, much to the delight of the majority inside the famous stadium.
"No [I wouldn't sign Kane]", McManaman said.
"It's not the last game or the final where you would say, 'OK, after that it's holidays'".
"We knew if we were solid at the back we would get chances and with the team we've got here we don't just want to compete, we want to be winning".
Kane, who has scored 13 goals in 12 appearances in all competitions for Spurs this season, missed defeats by West Ham United and Manchester United after suffering a minor hamstring strain. And it came as very little surprise when shortly before the half-hour mark Spurs took the lead. Today and yesterday was good at training.
Despite Kane's willingness, it is believed that Cristiano Ronaldo doesn't want to see the Spurs striker come to the Bernabeu.
Reason? Both clubs seem to be mirroring each other's results which is not something common in modern day football. He has no intentions of leaving the star status and play for a club like Real.
It was almost as if pundits and journalists were waiting for Spurs to trip up so that they could wheel out what I believe is now an inaccurate assessment.
Real Madrid make only one change from the shock defeat at Girona on Sunday, with Nacho coming in for Raphael Varane.
Revenge aside, this type of opportunity rarely comes knocking and Pochettino's men will do their utmost to capitalize.